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Fremdmoleküle in Zellen einbringen

Nanoinjektion: Kleiner Stich, große Wirkung

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Firmen zum Thema


[1] Neumann, E.; Schaefer-Ridder, M.; Wang, Y.; Hofschneider, P. H. Gene Transfer into Mouse Lyoma Cells by Electroporation in High Electric Fields. EMBO J 1982, 1, 841-5.

[2] McNeil, P. et al. Glass Beads Load Macromolecules into Living Cells. J Cell Sci 1987, 88 ( Pt 5), 669-78.


[3] Tsukakoshi, M.; Kurata, S.; Nomiya, Y.; Ikawa, Y.; Kasuya, T. A Novel Method of DNA Transfection by Laser Microbeam Cell Surgery. Appl Phys B-Photo 1984, 35, 135-140.

[4] Sharei, A et al. A Vector-Free Microfluidic Platform for Intracellular Delivery. Proc Natl Acad Sci U S A 2013, 110, 2082-7.

[5] Walev, I. et al. Delivery of proteins into living cells by reversible membrane permeabilization with streptolysin-O. PNAS 2001 98 (6) 3185-3190.

[6] Xu, J.; Teslaa, T.; Wu, T. H.; Chiou, P. Y.; Teitell, M. A.; Weiss, S. Nanoblade Delivery and Incorporation of Quantum Dot Conjugates into Tubulin Networks in Live Cells. Nano Lett 2012, 12, 5669-72.

[7] Hennig, S. et al. Instant live-cell super-resolution imaging of cellular structures by nanoinjection of fluorescent probes. Nano letters 15, 1374-1381, (2015).

[8] Simonis, M. et al. Survival rate of eukaryotic cells following electrophoretic nanoinjection Scientific Reports 7, 41277, (2017).

* *Dr. S. Hennig: Universität Bielefeld, Fakultät für Physik, Biomolecular Photonics, 33615 Bielefeld